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Weekly Readout

A digest of new clinical data from the past week.

These include…

landmark FDA approvals:

  • 1st FDA-approval for genetic hearing loss

  • 1st FDA-approval for PROTACs

potentially first-in-disease medicines, based on positive clinical data:

  • 1st successful Phase 3 trial for an in vivo CRISPR gene-editing therapy (link)

  • 1st successful Phase 3 trial for oral non-hormonal treatment for hair loss in nearly 30 year

potentially best-in-disease or best-in-class medicines, based on positive clinical data:

  • For plaque psoriasis

Frontiers in Medicine

Exploring the frontiers of our understanding and treatments for disease.

These include…

  • Obesity (Part 1, Part 2)

Acquisitions

Exploring the innovation behind acquired companies.

These include…

scientist-founded companies, which start with the foundational work of a researcher and organically grow into a biotech company:

  • Chiesi to Acquire KalVista, an oral HAE play

  • Eli Lilly to Acquire Ajax, a differentiated JAK play

entrepreneur-led asset aggregators, which are focused on building a pipeline of licensed drugs that are ‘potentially better versions’ of other drugs that have already achieved clinical/commercial success:

  • UCB to Acquire Candid, scooping a reverse merger for a TCE pipeline